国产欧美日韩三级_歐美日韓精品一區二區三區視頻播放_成年黄页网站大全免费无码_国产乱伦自拍无码_波野多结衣一区二区三区尤物视频_色综合久久婷婷_午夜一级**片不卡_7080理论片午夜电影在线_日韩少妇人妻中文视频_亚洲A色在线视频

Small interfering RNAs (siRNAs) are short double-strand RNA molecues less than 30 nt long. Once in the cells, they are loaded to enzyme complexes, which can recognize complimentary mRNA sequences and degrade them to achieve therapeutic effects.

siRNA drugs can be developed based on platform technologies. Their sequences are complementary to target mRNA according to base-pairing rules. Almost all genes can be down-regulated by siRNA, including traditionally undruggable targets. Combining with tissue-specific platform delivery technologies and chemical modifications, the potency, duration, and toxicity profile of siRNA drugs can be significantly improved. Thus, siRNA drugs can be developed a lot faster with much higher success rate. Super long-lasting efficacy and superb drug safety make them especially ideal for the treatment of chronic diseases and for certain rare diseases.

SiranBio has built industry-leading platforms which can support entire process of siRNA drug discovery and clinical translation. Our platforms include target validation, siRNA sequence synthesis and screening, chemical modification and targeting, and in vitro / in vivo assays.